Name: Septic shock - pathophysiology and symptoms | NCLEX-RN | Khan Academy
Uploaded: 2018-06-13T14:14:50.000Z
Duration: 10 min
Description: Thousands of YouTube videos with English-Chinese subtitles! Now you can learn to understand native speakers, expand your vocabulary, and improve your pronunciation...

- Septic shock is a
very serious condition.

About half the patients
who have septic shock

will die within the first
month of their diagnosis.

Septic comes from the old
Latin term meaning "rotten",

decreased tissue oxygenation
and low blood pressure.

So combined, it's decreased
tissue oxygenation

transfer oxygen, this
little purple substance

White blood cells will encounter
this infective material

whether it's bacteria,
virus, or a fungal infection,

So now your blood vessels are like pipes,

Of course when white blood cells encounter

When they activate,
there are several things

white blood cells to
come and check this out,

as many white blood cells to wherever this

infective material is
so you can eradicate it.

it's usually out here in
the interstitial tissue.

into the interstitial tissue
and eliminate the threat.

White blood cells do that
by releasing molecules,

interact with the blood vessels, and cause

Or in other words, the
diameter of the blood vessel

So let me go ahead and erase some of this

so we can show the dilation
of the blood vessel.

and now, blood vessel diameter increases.

This causes a localized
decrease in vascular resistance,

The blood, all of the blood
contents, have more space

to move around, and there's
less resistance that

they're bumping up
against, because of this

Of course, this makes
sense if this is happening

Because remember, the
immune system usually

encounters infective material
in the peripheral tissues.

To be able to get into
the peripheral tissues,

white blood cells need to
make the blood vessels leaky.

So that's the second thing
that's happening here.

Increase diameter and
increase permeability,

in the blood vessels
all throughout the body,

systemic vascular
dilation, or vasodilation.

This decrease in vascular
resistance causes

a drop in blood pressure,
because remember,

because the equation for tissue perfusion

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Septic shock - pathophysiology and symptoms | NCLEX-RN | Khan Academy

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